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Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

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Nanoscale Horiz., 2021, Advance Article
DOI: 10.1039/D0NH00624F, Communication
Byungji Kim, Qinglin Yang, Leslie W. Chan, Sangeeta N. Bhatia, Erkki Ruoslahti, Michael J. Sailor
RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.
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