Nanoscale Horiz., 2021, Advance Article
DOI: 10.1039/D0NH00588F, Communication
DOI: 10.1039/D0NH00588F, Communication
Yun Liu, Karthik Tiruthani, Menglin Wang, Xuefei Zhou, Nasha Qiu, Yang Xiong, Chad V. Pecot, Rihe Liu, Leaf Huang
In breast cancer model, we identified C–C Motif Chemokine Ligand 2 (CCL2) as the key mediator which is secreted by tumor associated adipocytes, and developed targeted lipid-protamine-DNA (LPD) nanoparticles to locally “trap” CCL2 to ameliorate the immunosuppressive tumor microenvironment.
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In breast cancer model, we identified C–C Motif Chemokine Ligand 2 (CCL2) as the key mediator which is secreted by tumor associated adipocytes, and developed targeted lipid-protamine-DNA (LPD) nanoparticles to locally “trap” CCL2 to ameliorate the immunosuppressive tumor microenvironment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry