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Endosome/lysosome-detained supramolecular nanogels as an efflux retarder and autophagy inhibitor for repeated photodynamic therapy of multidrug-resistant cancer

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Nanoscale Horiz., 2019, Accepted Manuscript
DOI: 10.1039/C9NH00643E, Communication
Xiaodong Zhang, Xiaokai Chen, Yuxin Guo, Hao-Ran Jia, Yao-Wen Jiang, Fu-Gen Wu
The presence of drug efflux pumps and endo/lysosomal entrapment phenomenon in multidrug-resistant cancer cells leads to insufficient and off-target accumulation of anticancer drugs in the cells, which severely reduces the...
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