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Enhancing subcutaneous injection and target tissue accumulation of nanoparticles via co-administration with macropinocytosis inhibitory nanoparticles (MiNP)

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Nanoscale Horiz., 2021, Advance Article
DOI: 10.1039/D0NH00679C, Communication
Trevor Stack, Yugang Liu, Molly Frey, Sharan Bobbala, Michael Vincent, Evan Scott
Macropinocytosis inhibitory nanoparticles reduce non-specific uptake of an “effector” nanoparticle by cells of the mononuclear phagocyte system thereby, allowing for greater accumulation and uptake of targeted nanoparticles in tissues of interest.
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