Encapsulation of polyprodrugs enables an efficient and controlled release of dexamethasone

Nanoscale Horiz., 2021, Accepted Manuscript
DOI: 10.1039/D1NH00266J, Communication

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Mengyi Li, Shuai Jiang, Adelina Haller, Sebastian Wirsching, Michael Fichter, Johanna Simon, Manfred Wagner, Volker Mailänder, Stephan Gehring, Daniel Crespy, Katharina Landfester
Water-soluble low molecular weight drugs, such as the synthetic gluococorticoid dexamethasone (DXM), can easily leak out of nanocarriers after encapsulation due to their hydrophilic nature and small size. This can...
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