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Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions

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Nanoscale Horiz., 2021, Advance Article
DOI: 10.1039/D0NH00550A, Communication
Open Access Open Access
Luís Estronca, Vitor Francisco, Patrícia Pitrez, Inês Honório, Lara Carvalho, Helena Vazão, Josephine Blersch, Akhilesh Rai, Xavier Nissan, Ulrich Simon, Mário Grãos, Leonor Saúde, Lino Ferreira
The vascular bioactivity/safety of nanomaterials is typically evaluated by animal testing, which is of low throughput and does not account for biological differences between animals and humans such as ageing, metabolism and disease profiles.
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