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Artificial intelligence in nanomedicine

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00233A, Minireview
Dean Ho, Peter Wang, Theodore Kee
The field of nanomedicine had made substantial strides in the areas of therapeutic and diagnostic development. For example, nanoparticle-modified drug compounds and imaging agents have resulted in markedly enhanced treatment...
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Enhancing potassium-ion battery performance by defect and interlayer engineering

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00305J, Communication
Yang Xu, Farzaneh Bahmani, Min Zhou, Yueliang Li, Chenglin Zhang, Feng Liang, Sayed Habib Kazemi, Ute Kaiser, Guowen Meng, Yong Lei
Defect and interlayer engineering is applied to exploit the large van der Waals gaps of transition metal dichalcogenides for potassium-ion batteries (KIBs). As a demonstrator, MoS2 nanoflowers with expanded interlayer...
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Photonic Cancer Nanomedicine at Near Infrared-II Biowindow Enabled by Biocompatible Titanium Nitride Nanoplatforms

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00299A, Communication
Chunmei Wang, Dai Chen, Zhongqian Hu, Hongqiang Li, Luodan Yu, Han Lin, Jianwen Bai, Yu Chen
Light-activated photoacoustic imaging (PAI) and photothermal therapy (PTT) in the second near-infrared biowindow (NIR-II, 1000-1350 nm) holds great promise for efficient tumor detection and diagnostic imaging-guided photonic nanomedicine. In this...
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Graphene Oxide Touches Blood: In Vivo Interactions of Bio-Coronated 2D Materials

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00318A, Review Article
Valentina Palmieri, Giordano Perini, Marco De Spirito, Massimiliano Papi
Graphene oxide is the hot topic of biomedical and pharmaceutical research of this decade. However, its complex interactions with human blood components complicate a transition of the promising in vitro...
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Tumour microenvironment-responsive semiconducting polymer-based self-assembly nanotheranostics

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00307F, Communication
Zhen Yang, Yunlu Dai, Lingling Shan, Zheyu Shen, Zhantong Wang, Bryant Yung, Orit Jacobson, Yijing Liu, Wei Tang, Sheng Wang, Lisen Lin, Gang Niu, Pintong Huang, Xiaoyuan Shawn Chen
A Pt prodrug polyphenol and gadolinium ion loaded cancer theranostics nanoplatform based on mild acidic pH and thermal sensitive polymer were designed for photoacoustic (PA)/ magnetic resonance(MR)/ positron emission tomography...
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High-temperature driven inter-valley carrier transfer and significant fluorescence enhancement in multilayer WS2

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Nanoscale Horiz., 2018, 3,598-605
DOI: 10.1039/C8NH00123E, Communication
Heyu Chen, Yuanzheng Li, Weizhen Liu, Haiyang Xu, Guochun Yang, Jia Shi, Qiushi Feng, Tong Yu, Xinfeng Liu, Yichun Liu
A high-temperature driven carrier transfer process of multilayer WS2 is proposed and demonstrated for significant fluorescence emission enhancement.
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Separating and enhancing the green and red emissions of NaYF4:Yb3+/Er3+ by sandwiching them into photonic crystals with different bandgaps

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Nanoscale Horiz., 2018, 3,616-623
DOI: 10.1039/C8NH00136G, Communication
Baoqi Liu, Zhipeng Meng, Suli Wu, Yue Wu, Shufen Zhang
Rational control of the multiple emission outputs and achieving single-band and strong luminescence of Ln3+ doped upconversion nanoparticles is highly desirable for their applications in sensor and display fields.
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Au3Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents

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Nanoscale Horiz., 2018, 3,624-631
DOI: 10.1039/C8NH00135A, Communication
Zhiyi Wang, Yanmin Ju, Shiyan Tong, Hongchen Zhang, Jian Lin, Baodui Wang, Yanglong Hou
Au3Cu tetrapod nanocrystals were synthesized. After surface modification, the obtained monodisperse Au3Cu@PEG-Cy5,FA showed great potential as a fluorescence imaging and MSOT imaging-guided photothermal agent in the NIR-II region, which could be metabolized in vitro after treatment.
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A tumor treatment strategy based on biodegradable BSA@ZIF-8 for simultaneously ablating tumors and inhibiting infection

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Nanoscale Horiz., 2018, 3,606-615
DOI: 10.1039/C8NH00113H, Communication
Qiong Wu, Mei Li, Longfei Tan, Jie Yu, Zengzhen Chen, Liuhui Su, Xiangling Ren, Changhui Fu, Jun Ren, Laifeng Li, Feng Cao, Ping Liang, Yu Zhang, Xianwei Meng
Biodegradable BSA@ZIF-8 can treat cancer by tumor microwave ablation, while simultaneously inhibiting bacteria and resisting infection.
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Novel properties and applications of carbon nanodots

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Nanoscale Horiz., 2018, 3,565-597
DOI: 10.1039/C8NH00106E, Review Article
Lian Xiao, Handong Sun
Overview of the optical properties and versatile applications of carbon dots.
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Site-specific surface tailoring for metal ion selectivity via under-coordinated structure engineering

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Nanoscale Horiz., 2018, 3,632-639
DOI: 10.1039/C8NH00094H, Communication
Li Yu, Gong Zhang, Chunlei Liu, Huachun Lan, Huijuan Liu, Jiuhui Qu
Engineering under-coordinated manganese simultaneously contributes to the exposure of hydroxylated edge sites and decreases the proportions of OVSs, enabling high-selectivity Pb(II)-sequestration.
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A location- and sharpness-specific tactile electronic skin based on staircase-like nanowire patches

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Nanoscale Horiz., 2018, 3,640-647
DOI: 10.1039/C8NH00125A, Communication
Shu Gong, Yan Wang, Lim Wei Yap, Yunzhi Ling, Yunmeng Zhao, Dashen Dong, Qianqian Shi, Yiyi Liu, Hemayet Uddin, Wenlong Cheng
A new stretchable tactile electronic skin sensor that could sense touch, location and sharpness is presented.
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Au Quantum-Dots Engineered Room Temperature Crystallization and Magnetic Anisotropy in CoFe2O4 Thin Film

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Nanoscale Horiz., 2018, Accepted Manuscript
DOI: 10.1039/C8NH00278A, Communication
Sagar Eknathrao Shirsath, Xiaoxi Liu, Hussein Naseef Assadi, Adnan Younis, Yukiko Yasukawa, Sumanta Kumar Karan, Ji Zhang, Jeonghun Kim, Danyang Wang, Akimitsu Morisako, Yusuke Yamauchi, Sean Li
This work for the first time unfurls a novel room temperature time-effective concept to manipulate the crystallization kinetics and magnetic response of thin films grown on amorphous substrate. Conventionally, metal...
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An enhanced enzymatic reaction using a triphase system based on superhydrophobic mesoporous nanowire arrays

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00184G, Communication
Fengying Guan, Jun Zhang, Heming Tang, Liping Chen, Xinjian Feng
Gaseous reactants play a key role in a wide range of biocatalytic reactions, however reaction kinetics are generally limited by the slow mass transport of gases (typically oxygen) in or through aqueous solutions. Herein we address this limitation by developing a triphase reaction system.
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Fully integrated hierarchical double-shelled Co9S8@CNT nanostructures with unprecedented performance for Li–S batteries

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00289D, Communication
Jie Zhou, Xiaojing Liu, Jianbin Zhou, Haoyu Zhao, Ning Lin, Linqin Zhu, Yongchun Zhu, Gongming Wang, Yitai Qian
Fully integrated hierarchical double-shelled Co9S8@CNTs have been developed as a highly efficient sulfur cathode.
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Efficient hole transfer from monolayer WS2 to ultrathin amorphous black phosphorus

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00234G, Communication
Matthew Z. Bellus, Zhibin Yang, Peymon Zereshki, Jianhua Hao, Shu Ping Lau, Hui Zhao
Transient absorption measurement reveals ultrafast charge transfer from crystalline to amorphous two-dimensional semiconductors.
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A single-step multi-level supramolecular system for cancer sonotheranostics

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00276B, Communication
Huirong Lin, Shuang Li, Junqing Wang, Chengchao Chu, Yang Zhang, Xin Pang, Peng Lv, Xiaoyong Wang, Qingliang Zhao, Junjie Chen, Hongmin Chen, Wen Liu, Xiaoyuan Chen, Gang Liu
A multi-level supramolecular system produced by single-step Fe3+-mediated ionic crosslinking self-assembly can overcome the critical issues of current sonodynamic therapy (SDT) and address the need to monitor therapeutic effects in vivo with a non-invasive approach.
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Artificial intelligence in nanomedicine

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00233A, Minireview
Dean Ho, Peter Wang, Theodore Kee
Artificial intelligence is poised to substantially enhance the efficacy and safety of nanomedicine.
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Realizing the extraction of carbon from WC for in situ formation of W/WC heterostructures with efficient photoelectrochemical hydrogen evolution

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00275D, Communication
Zongkui Kou, Tingting Wang, Zonghua Pu, Lin Wu, Kai Xi, Shichun Mu
As a proof of concept, in this work we realize the extraction of carbon atoms from carbide lattices by rationally controlling the reaction between carbides and Cl2.
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Enhancing potassium-ion battery performance by defect and interlayer engineering

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Nanoscale Horiz., 2019, Advance Article
DOI: 10.1039/C8NH00305J, Communication
Yang Xu, Farzaneh Bahmani, Min Zhou, Yueliang Li, Chenglin Zhang, Feng Liang, Sayed Habib Kazemi, Ute Kaiser, Guowen Meng, Yong Lei
Expanded interlayer spacing and additionally exposed edges induced by defects of MoS2 enable facile K-intercalation, rapid K-transport and promoted K-adsorption.
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